The contents and requirements of core literacy in various disciplines are different and interrelated, and cannot be completely separated. As far as mathematics is concerned, the research shows that the core literacy of mathematics includes six aspects: mathematical abstraction, logical reasoning, mathematical modeling, mathematical operation, intuitive imagination and data analysis. The cultivation of the core literacy of mathematics should be carried out through subject teaching and comprehensive practical activity courses. First, mathematics teaching activities are the main way to cultivate mathematics literacy. The six aspects of mathematics core literacy have different requirements in five stages: primary school, junior high school, senior high school, junior college and postgraduate education, and so on. We should carefully scrutinize, accurately grasp and effectively run through the subject teaching activities. Second, the comprehensive practical activity course of inquiry learning is an important way to cultivate mathematics quality. Because inquiry learning is a comprehensive course, it must contain relevant knowledge of mathematics, and because of the characteristics of its practical activity course, it has higher requirements for mathematical modeling, mathematical abstraction and mathematical reasoning. Third, teenagers' scientific and technological innovation activities are a good way to cultivate mathematics quality. The National Youth Science and Technology Innovation Competition is a comprehensive science and technology competition with a history of more than 20 years. It is one of the demonstrative and instructive science and technology education activities for primary and secondary school students, and it is a concentrated display form of outstanding achievements of various science and technology activities in primary and secondary schools in China. The competition is divided into mathematics, physics, chemistry, microbiology and other research fields 13, which is scientific, advanced and practical. Cultivating and improving related mathematics subject literacy in activities can play a role that simple subject teaching is difficult to play. Fourthly, the general technology course is also an effective way to cultivate mathematics quality. The general technology course is based on practice, pays attention to creation, is comprehensive, and integrates science and humanities. In the course study and practice, it is bound to involve related mathematics core literacy, which complements other literacy, so that students' physical and mental quality can be fully and healthily developed.