Hefei No.1 Middle School, the full name of Hefei No.1 Middle School, is one of the well-known high schools with the longest history, the largest scale and the strongest comprehensive strength in Hefei, Anhui Province. 1897, the British missionary Schindler founded Anhui No.1 Normal School for Women, which later evolved into Wu Wen School, National Hefei Senior Vocational Middle School and Hefei No.2 Middle School, and was renamed in 1958.

At present, Hefei No.1 Middle School has developed into a junior middle school, a senior middle school and an international department, with various teaching and research institutions and top-quality courses, with a campus area of 305,000 square meters and a school building area of11.2000 square meters. At present, the school has more than 654.38 million students and nearly 1,000 faculty members.

As a national model high school and the first batch of key ordinary high schools in Anhui Province, Hefei No.1 Middle School has always adhered to the school-running philosophy of "taking quality education as the core, curriculum as the foundation and educating people as the center". The school pays attention to students' individualized development and character cultivation, and has formed its own educational characteristics in the fields of culture, art, sports, science and technology, and won many national and provincial awards. In addition, the school's international curriculum solution course has also been well received, and it has established a friendly exchange relationship with high schools in 19 countries.

Sanxiaokou Campus of Hefei No.1 Middle School is expected to return to Hefei No.1 Middle School in 2024 and be set as "Changjiang Road Campus". This move is to keep a homesickness of China people. According to the plan, the old campus in Sanxiaokou will be reused by Hefei No.1 Middle School and become a part of the group's strategy. Hefei No.1 Middle School will form a pattern of "one school and four districts", namely, Binhu Campus of Binhu New District, Changjiang Road Campus, Hefei No.1 Middle School East Campus, the core area of Yaohai East New Center, and Hefei No.1 Middle School He Fei Campus in Hefei District.