Bio-mathematics has a rich mathematical theoretical basis, including set theory, probability theory, statistical mathematics, game theory, calculus, differential equations, linear algebra, matrix theory, topology, and some branches of modern algebra, such as information theory, graph theory, cybernetics, system theory and fuzzy mathematics. Because of the complexity of life phenomena, the mathematical problems raised from biology are often very complicated and require a lot of calculation work. Therefore, computer is the basis of the emergence and development of biomathematics, and it has become an important tool to study and solve biological problems. But as far as the content of the whole subject is concerned, the essential aspect that biomathematics needs to solve and study is biological problems, and mathematics and computers are just tools and means to solve problems. Therefore, biomathematics, like other frontier disciplines, is usually classified as biology rather than mathematics.