The application of biotechnology is generally science or engineering, and the best is more. However, there are also some colleges and universities that take the number three exam. There are still many schools that don't take math exams, especially science classes.
In the enrollment brochure of the school you apply for, there will be detailed instructions to tell you how to take the math test.
The difference between "one, two and three" in mathematics lies in the different objects, and the content and difficulty of the exam are slightly different, which is usually understood as "one is the most difficult and three is the easiest".
As for the outline of the examination content, it was issued by the Examination Management Center of the Ministry of Education. You can download it online or buy it in a bookstore. It is unrealistic for me to type it for you here, because this answer box can't input so many words.