Xiao Wu, who works in a training institution, was found to be virus-negative in a physical examination about ten years ago. The local doctor suggested checking liver function, HBV DNA and B-ultrasound every six months. Ms Wu is very concerned about this matter. She will go to the hospital every six months. It's no big deal to check for three years in a row. Thinking that it was a waste of money anyway, she didn't go to the hospital.
Some time ago, Ms. Wu suffered from unexplained loss of appetite and abdominal distension, and she was unable to lift her spirits at work. She thought it was caused by some fatigue from recent work pressure and didn't take it seriously. However, for nearly half a month, the symptoms have not been alleviated. Ms. Wu felt a little worried, so she went to the hospital for a comprehensive examination of liver function, blood routine, color Doppler ultrasound and alpha-fetoprotein. It turned out to be liver cancer. Ms. Wu regretted not having regular inspections in order to save money. Everyone must not take the old path of Ms. Wu and check regularly according to the doctor's advice.
1, liver function test
Liver function examination is a very important examination, which can detect whether the physiological function of the liver is abnormal. For patients with hepatitis B, when the liver function is abnormal, it is necessary to carry out liver protection and enzyme reduction treatment. At this time, if the hbv-dna test is positive, antiviral treatment is needed.
2. Five hepatitis B tests
Five tests of hepatitis B can be divided into qualitative and quantitative tests. Qualitative examination can detect whether patients are infected with hepatitis B and distinguish between hepatitis B big three positive and hepatitis B small three positive. Quantitative examination is better than qualitative examination. Through the five quantitative analysis of hepatitis B, it not only has the function of qualitative examination, but also provides the accurate content of hepatitis B virus markers. In fact, the level is a reliable basis for diagnosing hepatitis B. In addition, healthy people produce reactive antibodies after completing hepatitis B vaccine injection, and the degree of antibody production can be known by quantitatively detecting the concentration of anti -HBs. A high concentration of anti -HBs indicates that the vaccine injection is successful, and a low concentration or even undetectable indicates that the vaccine injection effect is poor or ineffective.
3.HBV-DNA test
In addition to liver function and hepatitis B, HBV-DNA detection is also an important examination for patients with hepatitis B. The purpose of HBV-DNA detection is mainly to judge the degree of virus replication and infectivity of patients at present, which plays an important role in judging the prognosis of hepatitis B and the curative effect before and after medication, and is also one of the important indications for medication, especially antiviral treatment. 、
4.b-ultrasound examination
There are many liver function tests in clinic, but there are some limitations in simply passing the liver function test. Because the liver has a strong compensatory ability, normal liver function does not mean that the liver is not damaged. If B-ultrasound shows moderate or severe liver injury, it also needs treatment. In addition, B-ultrasound can also determine whether the disease has turned into cirrhosis or whether there is a space-occupying lesion.
5, alpha-fetoprotein
Hepatitis A-AFP rarely rises, even if it rises, it rarely exceeds 200 nanograms. However, alpha-fetoprotein in liver cancer is often greater than 400 nanograms. If alpha-fetoprotein continues to decrease and remains above 400 ng, we should pay attention to the possibility of liver cancer.
6, liver fibrosis index
The degree of liver fibrosis can be preliminarily judged by blood tests of serum type ⅲ procollagen, laminin, hyaluronic acid and type ⅳ collagen.