1. 1 Definition of biodegradation

Biodegradation mechanism of 1.2

1.2. 1 solubilization

1.2.2 generates charge.

1.2.3 chemical hydrolysis

1.2.4 enzymatic hydrolysis

1.3 biodegradable drug delivery system

1.3. 1 diffusion control system

1.3.2 expansion control system

1.3.3 biodegradable system

1.4 biodegradable polymer

refer to

Chapter II Chemically Synthesized Biodegradable Polymers

2. 1 polylactic acid and polyglycolic acid

2. 1. 1 Overview

2. 1.2 attribute

2. 1.3 preparation of polylactic acid and polyglycolide

2. 1.4 biodegradation

2. 1.5 biocompatibility

2. 1.6 preparation technology

2. 1.7 product sterilization technology

2. 1.8 application

2.2 Polycyanoacrylate

2.2. 1 Synthesis of Cyanoacrylate Monomer

2.2.2 Synthesis and Characterization of Polycyanoacrylate

2.2.3 Degradation of Polycyanoacrylate

application program

2.3 Polycaprolactone

2.3. Preparation of1polycaprolactone and its polymer

2.3.2 Characterization of Polycaprolactone and Its Polymers

process

degenerate

application program

2.4 Poly (p-dioxanone) and its * * * polymer

2.4. 1 overview

2.4.2 Synthesis of p-dioxanone

2.4.3 Poly (p-dioxanone) homopolymer

2.4.4 Poly (p-dioxanone) polymer

2.5 polyanhydride

2.5. 1 synthesis

Structure of polyanhydride

Characterization of polyanhydride

2.5.4 Stability of Polyanhydride

2.5.5 Preparation of drug delivery device

2.5.6 Degradability and biocompatibility

2.5.7 Application of Polyanhydride

2.6 polosham

2.6. 1 overview

2.6.2 Characteristics of Poland

2.6.3 Toxicology of poloxamer

Polosham 188

Polosham 407

2.6.6 poloxamer 33 1, 334 and 338

2.7 Poly (1, 2- propylene fumarate)

2.7. 1 synthesis

Characterization and application

2.8 Polyphosphazene

polyphosphazene

2.8.2 Synthesis of Polyphosphazene

Application of polyphosphazene

2.8.4 Biocompatibility of Polyphosphazene

2.9 l-tyrosine derived polymer

Tyrosine-derived polycarbonate

2.9.2 polyaromatic compounds derived from tyrosine

2.9.3 Polyurethane Carbonate Derived from Tyrosine

2. 10 polyorthoester

Polyorthoester 1

Polyorthoester II

2. 10.3 polyorthoester III

Polyorthoester IV

2. 1 1 Other polyesters and amino acid polymers

2. 1 1. 1 polyether ester

2. 1 1.2 polyesteramide

2. 1 1.3 polyether urethane

2. 1 1.4 polyphosphate

2. 1 1.5 amino acid polymer

refer to

Chapter 3 Biosynthesis of Biodegradable Polymer

3. 1 genetically engineered protein polymer

3. Preparation of1.1protein polymer

3. Properties and Characterization of1.2 protein Polymer

3. 1.3 material characteristics and processing

3. 1.4 Biological characteristics

3.2 Conductive elastic and plastic protein-based polymers

3.2. 1 synthesis

Feature description

application program

3.3 polyhydroxyalkanoate

3.3. 1 PHA biosynthesis

3.3.2 Physical properties of polyhydroxyalkanoate

3.3.3 Biodegradation of polyhydroxyalkanoate

refer to

Chapter 4 Natural and Semisynthetic Biodegradable Polymers

4. 1 natural polysaccharide and modified polysaccharide

4. 1. 1 chemical modification

4. 1.2 biodegradation

4. 1.3 Attribute and Application

4.2 oxidized cellulose

4.2. 1 No? 2 oxidation

4.2.2 Biodegradation

4.2.3 Bioabsorption

application program

4.3 fibrinogen and fibrin

4.3. 1 separation method

4.3.2 Characterization of fibrinogen

4.3.3 Characterization of Fibrin Polymerization and Coagulation

Fibrinolysis

4.3.5 Clinical application

safe

4.4 Collagen

4.4.65438+Preparation of Type I Collagen

4.4.2 Processing and molding of collagen

4.4.3 Stability of Collagen Products

4.4.4 Packaging and sterilization of collagen products

4.4.5 Safety Verification of Collagen Products

4.4.6 immunogenicity of collagen

application program

4.5 Gelatin

4.5. 1 chemical composition and structure

4.5.2 Physical and chemical characteristics

Preparation and processing

4.5.4 Identification of gelatin

application program

refer to

Chapter 5 Biodegradable Hydrogels

5. 1 overview

5.2 Structure and Properties of Biodegradable Hydrogels

5.2. 1 structure

5.2.2 Surface characteristics and biocompatibility

Water in hydrogel

5.3 Physical Hydrogels

5.3. 1 Thermoreversible Gel

5.3.2 Thermoreversible Gel Polysaccharide

Ionic coordination gelation

5.3.4 Gelation caused by specific action

5.4 Chemical Hydrogels

5.4. 1 water-soluble monomer and crosslinking agent * * * polymerization

5.4.2 Crosslinking of Water-soluble Polymers

5.5 Degradation of Hydrogel

Chemically induced degradation

Enzymatic hydrolysis

5.6 Application of Biodegradable Hydrogels

5.6. 1 drug loading

Albumin microspheres

Gelatin trace

Starch microspheres

Dextran microspheres

refer to