Compendium of Materia Medica is a masterpiece of pharmacology written by Li Shizhen in Ming Dynasty, with 52 volumes, 1892 drugs. This book is a comprehensive arrangement and supplement of China's ancient materia medica, which has a far-reaching impact on the development of later medicine.

Compendium of Materia Medica in Qing Dynasty is included in Sikuquanshu, which is the largest series in ancient China, including all kinds of important works in ancient and modern times. Sikuquanshu is divided into four sub-parts: classics and history, among which the sub-part contains medical health-preserving works, and Compendium of Materia Medica is among them, which shows its important position.