Solution: Solution: Of the five cards, 3 are odd and 2 are even; Take out 2 pieces, *** 10 method; Among them, even number and 4 kinds, odd number and 6 kinds; So the probability of Xiao Ming winning is 0.6, and the probability of Xiao Hong winning is 0.4, so the game is unfair and Xiao Ming wins easily.
Comments: This question examines the judgment of the fairness of the game. To judge the fairness of the game, it is necessary to calculate the probability of each event. If the probability is equal, it is fair, otherwise it is unfair. The knowledge points used are: probability = the ratio of the number of required cases to the total number of cases.