After Helicobacter pylori enters the stomach, it passes through the mucus layer with the help of flagella on one side of the bacteria. Studies have shown that Helicobacter pylori has strong exercise ability in viscous environment, and strong exercise ability is an important factor in the pathogenesis of Helicobacter pylori. After Helicobacter pylori reaches the epithelial surface, it is firmly connected with epithelial cells through adhesin to avoid being emptied by the stomach with food. It secretes superoxide dismutase and catalase to protect it from the killing effect of neutrophils. Helicobacter pylori is rich in urease, which hydrolyzes urea to produce ammonia, forming an "ammonia cloud" protective layer around bacteria to resist the killing effect of gastric acid.

The main causes of Helicobacter pylori infection are as follows:

1, unclean diet

Helicobacter pylori may remain in raw meat. If you often eat undercooked steak, or eat hot pot, eat it directly if it is not cooked, and it is more likely to cause helicobacter infection after entering the stomach. In order to avoid the infection of Helicobacter pylori, everyone should pay attention to controlling diet, ensuring the hygiene of diet and avoiding bacterial infection.

2, spicy

Many people like to eat pungent food, which leads to gastrointestinal irritation and affects the resistance of gastrointestinal mucosa. If you eat unclean food, it will often cause the harm of Helicobacter pylori, leading to a variety of gastrointestinal diseases.

3, * * * meal

The main route of transmission of Helicobacter pylori is oral transmission. Family members have symptoms of Helicobacter pylori infection, which may appear during meals, causing other family members to have similar symptoms. Especially for people who often eat out, the probability of infection will greatly increase.

4. Kissing

Helicobacter pylori may also exist in saliva. If you don't pay attention to the hygiene of kissing, it will lead to cross infection.

5. Spleen deficiency

If people are tired for a long time or have an uncoordinated diet, it will cause spleen deficiency. Once stimulated by the outside world, the resistance is greatly reduced. After contact with Helicobacter pylori, it can cause various diseases of internal organs, including chronic gastritis and splenism.