It is reported that the incidence of pancreatitis is in frederickson.

Type ⅰ hyperlipidemia was 30%, type ⅳ hyperlipidemia was 15%, and type ⅴ hyperlipidemia was 27%-4 1%. Because type ⅳ hyperlipidemia is the most common, hyperlipidemia is more important in the etiology of acute pancreatitis.

The mechanism of hyperlipidemia complicated with pancreatitis is not clear. Could be:

1, the blood viscosity increases, leading to pancreatic circulation disorder and pancreatic hypoxia;

2. Pancreatic blood vessels were embolized by concentrated fat, and the pancreas was ischemic and necrotic;

3. The pancreas is infiltrated by fat;

4. Triglycerides are decomposed by lipase to form toxic free fatty acids, which destroy the walls of small blood vessels and promote the formation of microthrombosis.

At present, it is considered that the blood triglyceride reaches11.25-22.58 mmol/L, which is easy to cause acute pancreatitis. There are many factors that cause hyperlipidemia. Besides heredity and diet, alcohol, pregnancy, oral contraceptives, long-term use of estrogen and vitamin A can all cause it, which should be paid attention to.

Hyperlipidemia often occurs in acute pancreatitis. Hypertriglyceridemia may be the cause of acute pancreatitis, but moderate increase may also be the result of acute pancreatitis. Despite the above facts, most published human studies have found that intravenous fat injection will not cause pancreatic exocrine and will not aggravate the disease. In addition to hyperlipidemia pancreatitis, fat emulsion (MCT/LCT is better) should be used intravenously. Therefore, under the premise of strictly detecting the plasma fat clearance rate of patients, most scholars have accepted that intravenous infusion of fat emulsion is safe.