COVID-19 usually refers to novel coronavirus infection, and the mortality rate of novel coronavirus infection is about 8/ 100000, that is, there may be 8 deaths among nearly100000 people. However, novel coronavirus infection is influenced by many factors, and it cannot be generally considered that novel coronavirus infection caused death. At present, the infection rate and mortality rate in COVID-19 are mainly budgeted by mathematical models; Different values set in the mathematical model will lead to different prediction results. For example, Wu Zunyou predicted that the epidemic infection rate in COVID-19 this winter would be 10%-30% and the mortality rate would be 0.09%-0. 16%, while Feng Zijian predicted that the infection rate in the first wave of peak population would reach about 60% and eventually reach 80%-90%.