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Is there a requirement for mathematics in learning bioinformatics?
Strictly speaking, biological information requires a lot of mathematics, but how high it is depends on the specific work.

Generally speaking, the simple biological information on the Internet is miscellaneous fish that do sequencing and run the process in the company. These people know nothing about the work in their hands. Fortunately, the first thing in the development of general bioinformatics software is to ensure that researchers who don't know computers can adapt, so most of them are fools.

But the failure of mathematics is a big bottleneck for those who do bioinformatics research, because the greatest bioinformatics fields fall on mathematics, physics and chemistry, and all the applications you see are actually the biological applications of the theories in these fields. As a result, researchers in the field of pure biology know almost nothing about the theoretical knowledge of biological information, and non-fool software, especially software that has to set a large number of parameters by itself, is hardly suitable for them. Because you will find that you have never heard of all the parameters in those softwares, and the documents you find are all mathematical formulas that everyone can understand.

Having said that, I finally tell you that mathematics is very important, even if you don't interrupt your entry into the development field, you can ensure the smooth work in the future. As for what to look at, it depends on the specific direction of work in the future. The theoretical background of different directions may be completely different, so it is better to discuss it when there is specific work.