But the failure of mathematics is a big bottleneck for those who do bioinformatics research, because the greatest bioinformatics fields fall on mathematics, physics and chemistry, and all the applications you see are actually the biological applications of the theories in these fields. As a result, researchers in the field of pure biology know almost nothing about the theoretical knowledge of biological information, and non-fool software, especially software that has to set a large number of parameters by itself, is hardly suitable for them. Because you will find that you have never heard of all the parameters in those softwares, and the documents you find are all mathematical formulas that everyone can understand. Having said that, I finally tell you that mathematics is very important, even if you don't interrupt your entry into the development field, you can ensure the smooth work in the future. As for what to see, it depends on your specific work direction in the future. The theoretical background of different directions may be completely different, so it is better to discuss it when you have specific work.