Physical chemistry is a branch of mathematics at a certain stage. Mathematical physics pays more attention to theoretical calculation, while chemistry is developed on the basis of teaching some common phenomena in life. At first, chemistry paid attention to phenomena and experiments. With the deepening of research, some practical essences in chemistry must be explained by formulas and theories in mathematical physics. For example, both quantum chemistry and physical chemistry are based on mathematics and physics.

Without mathematics, physical chemistry can only be in the stage of empirical experiments, and the real essence will never be known.