Zhu is one of the earliest pharmacologists in China. He did a lot of work in pharmacological research in his early years and initiated mathematical pharmacology research in his later years. As early as 1925, Zhu taught pharmacology at Xiangya Medical College and served as an associate professor of pharmacology. Then he successively engaged in pharmacology teaching and scientific research in Union Medical College, Shanghai Medical College and Zhejiang Medical College. During his tenure at Union Medical College, Chen Faxian's ephedrine research work gave him great inspiration, which made him realize that TCM research has great potential. Therefore, as early as the early 1930s, he cooperated with others and devoted himself to the pharmacological research of traditional Chinese medicine, and successively published papers such as Pharmacological Action of China Aconitum, Current Situation of Poisoning and Vomiting Action of Flos rhododendri mollis, Bronchial Components of Earthworms, Reversal Mechanism of Ephedrine's Hypotensive Action, etc. From 65438 to 0939, combined with his own teaching experience and research results, he compiled and published a textbook of Pharmacology, in which he devoted a chapter to the study of several traditional Chinese medicines, introducing the research results of nearly 20 kinds of traditional Chinese medicines, such as corydalis yanhusuo, ephedra, angelica sinensis, boneless wind, salvia miltiorrhiza, ginseng and Datura flower. This is the first pharmacology textbook compiled by China pharmacologists. Since 1950s, Zhu deeply felt that the relationship between pharmacology and advanced mathematics was getting closer and closer, and mathematical methods were becoming an indispensable tool for pharmacological research. From 65438 to 0959, when he was studying anti-schistosomiasis drugs, he first quantitatively analyzed and processed the dynamic changes of blood antimony concentration by mathematical methods, and calculated the pharmacokinetic indexes such as half-life and clearance rate. In 1960s, he was 70 years old, and he was still assiduously studying the receptor theory of pharmacological action mechanism, discussing the application prospect of statistical mechanics, quantum mechanics and quantum biochemistry in pharmacology, and further realizing that using mathematical methods in pharmacological research can effectively reveal a series of quantitative laws of pharmacology. 1963 He compiled his own experience into the article "Problems in Pharmacology" and personally read it out at the national academic conference on physiological science held in Dalian, pointing out: "Many problems in pharmacology, such as absorption, distribution, excretion and metabolism of drugs, mechanism of action of drugs, treatment of drug poisoning, adjustment of drug dosage, stability of drugs and verification of drugs, are being used more and more. Dealing with' quantity' is also inseparable from dynamics, thermodynamics and statistics. " He focused on the application of dynamics, thermodynamics and quantum mechanics in pharmacology, and predicted that the development of quantum chemistry would lead to quantum pharmacology. This is the first time that China pharmacologists have systematically expounded the new research direction of mathematical pharmacology (namely quantitative pharmacology). Quantum pharmacology has officially become a new branch of pharmacology, and its pharmacokinetics and pharmacodynamics have been popularized in China. From 65438 to 0982, the first national academic conference on mathematical pharmacology was held in Huangshan, and the kinetic problems in pharmacology were discussed. The old experts and professors attending the meeting recalled Zhu's report at the Dalian meeting, and all praised his foresight and thought that this meeting was the realization of his long-cherished dream for decades. He was unanimously elected honorary chairman of the National Committee of Mathematical Pharmacology. This is a full affirmation of his advocacy of quantitative pharmacology research.