The knowledge depth and specific application direction of medical advanced mathematics and advanced mathematics are different. Medical advanced mathematics is to provide medical workers and medical college students with necessary mathematical knowledge and common calculation methods, and enhance their data processing ability, logical thinking ability and ability to analyze and solve practical problems; Provide them with the necessary mathematical foundation for learning other subjects. Expand information 1. Expand knowledge. On the premise of ensuring the integrity of the theoretical system, the unary function calculus and differential equation are appropriately compressed, and the multivariate function calculus, linear algebra, probability theory, mathematical statistics, mathematical experiments and fuzzy mathematics are added. As an introduction to expand students' mathematical knowledge. 2. Reflect the medical characteristics, increase a large number of biological and medical examples, exercises and complete medical mathematical models, highlight the idea of using mathematical theory knowledge to solve medical problems, and emphasize practical principles.