algal polysaccharides

Report/correction

Algal polysaccharide mainly comes from kelp, Sargassum fusiforme (Sargassum), macroalgae, submerged algae, fucoidan and other algae. Algae polysaccharide mainly includes fucoidan, fucoidan and fucoidan starch. The crude products of fucoidan, fucoidan and fucoidan separated from kelp are all white and yellowish powders. The purified sodium alginate is white silk; Fucoidan is milky white powder; Both of them are soluble in water and insoluble in organic solvents such as ethanol, acetone and chloroform.

The purification of trehalose gum often adopts ethanol precipitation, quaternary ammonium salt precipitation, DEAE fiber column chromatography and gel column chromatography. The methods of purity identification include cellulose acetate film electrophoresis and dextran gel G-75 chromatography.

Trehalose gum has many physiological activities: (1) Crude polysaccharide, fucoidan and one of its high-purity components F4 extracted from kelp have a strong hypoglycemic effect; (2) Experiments show that laminarin sulfate has a stronger inhibitory effect on vascular activity than suramin, but it has certain toxic and side effects. (3) Studies in vitro and in vivo confirmed that sulfated polysaccharide from kelp has anti-tumor effect; (4) Xin Xianliang and others found that marine sulfated polysaccharide 9 1 1 can obviously inhibit the acute infection of HIV- 1 on MT4 cells and the chronic infection of H9 cells.

In addition, sulfated polysaccharides (carrageenan and fucoidan) and 1 sulfated monosaccharide glucosamine have significant anti-HIV- 1 activities in vitro, which confirms the antiviral activity of sulfate groups.