Perhaps the comic book "のぅぉとこ" was written by Japanese neurologist Junichi Watanabe, who introduced the knowledge about the brain and neuroscience in the form of humorous cartoons, including a detailed introduction to the brain nervous system and endocrine system. There are also some female characters in the comics, and one of them is called "Clothes-Dressed Girl", which may be what you call "a soft girl introducing her brain".