List of articles: 1. What is the efficacy and function of scalding leeches? 2. What is the effect of scalding leeches? 3. What is the efficacy and function of scalding leeches? 4. What are the indications for leeches? How to identify? 5. What is the function of leeches? How to use it? 6. What are the effects and functions of raw leech powder or scalded leeches? What effect and function does scalded leech have? 1, blood stasis amenorrhea, accumulation of accidents.
This product is salty and bitter, and has strong ability to break blood and remove blood stasis. Mainly used for blood stasis, amenorrhea, abdominal mass accumulation and other syndromes.
It is often used with tabanus, Rhizoma Sparganii, Rhizoma Curcumae, Semen Persicae and Flos Carthami, such as Didang Decoction (Treatise on Febrile Diseases). If the patient's constitution is weak, it can be combined with drugs such as ginseng and angelica to tonify qi and blood, such as "Garland Shenghuidan" in Treatise on Febrile Diseases.
2, traumatic injury, heart pain
This product has the function of breaking blood and removing blood stasis, and is also commonly used for traumatic injuries. It can be combined with hematoxylin and native copper, such as Jiegu Huolong Dan (Puji Formula).
For patients with blood stasis, pain in the heart and constipation, rhubarb and morning glory can be combined, such as Duoming Powder (Fang Jisheng).
The effect of fried leech is bitter, salty, flat and toxic.
Its main functions are to break blood, promote blood circulation and dissipate stagnation.
Modern research reports that leeches contain hirudin, which can delay and hinder blood coagulation, thus having anticoagulant effect.
This product has strong blood-breaking ability, and it is forbidden for pregnant women and those without severe blood stasis.
Efficacy and function of scalding leeches In recent years, with the deepening of research on leeches, leeches have been widely used in the treatment of cardiovascular and cerebrovascular diseases. This paper reviews the chemical constituents and pharmacological effects of leech.
Next, I will learn from you the efficacy and function of scalding leeches.
Efficacy of scalding leeches
① Effect of Leech on Vascular Endothelial Cells
Vascular endothelial cells have many biological functions. When endothelial cells are damaged for various reasons, their biological functions change and various diseases appear.
Modern medical research shows that leech can protect endothelial cells, avoid injury, maintain its function, and prevent and treat diseases caused by endothelial cell injury through various ways, and its action ways are mainly shown in the following aspects:
(1) on endothelial relaxing factor -ON (NO).
It has been confirmed that ON (nitric oxide) is the most important endothelium-derived vascular relaxing factor, which has the functions of relaxing blood vessels and resisting cell adhesion, and plays an important role in protecting endothelial cells.
Derived from arginine decomposition catalyzed by nitric oxide synthase (NOS) in endothelial cells.
(2) Effect on vascular permeability.
Vascular endothelial cells maintain their normal permeability and play an important role in the normal material exchange between blood and tissue fluid.
When endothelial cells are damaged for various reasons, their permeability will change and increase, and excessive substances in blood will enter vascular tissue, causing cardiovascular diseases.
Zhou et al. observed the effect of compound containing leech on the depth and permeability of Evans blue in vascular endothelium, and found that the compound could significantly inhibit the increase of endothelial cell permeability under high lipid state.
(3) Inhibit LPO (lipid peroxide) from damaging endothelial cells.
The increase of serum lipid peroxide caused by hyperlipidemia is an important cause of vascular endothelial injury, which accelerates the oxidation of EC (endothelial cells) to modify low-density lipoprotein and eventually forms AS (atherosclerosis).
② Effect on hemorheology.
Abnormal hemorheology is the basis of cardiovascular diseases.
Hyperlipidemia, hyperviscosity, hypercoagulability and erythrocyte aggregation are the common main causes of abnormal hemorheology, which can aggravate vascular endothelial injury and reduce microcirculation perfusion, and are important pathogenic factors of cardiovascular system.
Leech can not only reduce blood lipid, but also adjust the relative balance of PGI2/TXA2 in circulating plasma, and maintain the stability of internal environment, which provides a certain theoretical basis for leech to prevent and treat atherosclerosis and various cardiovascular diseases.
Hyperviscosity plays an important role in cardiovascular diseases such as arteriosclerosis, coronary heart disease and cerebral infarction. The decrease of erythrocyte deformability, the increase of aggregation and fibrinogen may be the important reasons for accelerating arteriosclerosis and thrombosis.
Therefore, reducing blood viscosity plays an important role in the prevention and treatment of cardiovascular diseases.
In recent years, it has been found that leeches contain many bioactive substances related to anticoagulation, such as hirudin, antithrombin and heparin. It has strong effects of inhibiting erythrocyte aggregation, anticoagulation and increasing microcirculation perfusion, and can obviously reduce blood viscosity.
③ Effect on platelets.
Adhesion, aggregation and release of platelets play an important role in the occurrence and development of thrombosis and atherosclerosis. As a method to prevent and treat cardiovascular and cerebrovascular diseases and other thromboembolic diseases, antiplatelet function has been paid more and more attention. In recent years, there are more and more reports about the inhibitory effect of leeches on platelets.
Modern research shows that the anticoagulant peptide of leech can inhibit platelet aggregation from two aspects:
Effect of (1) on platelet glycoprotein Ⅱ b Ⅲ a
(gp) Ⅱ b Ⅲ a receptor on platelet surface plays a decisive role in platelet aggregation. After platelet activation, (gp) Ⅱ b Ⅲ a receptor on the surface of platelet was expressed, and then fibrinogen was connected.
Fibrinogen, as a bivalent molecule, connects platelets with each other and constitutes a step of aggregation.
Any reagent that can disrupt the interaction of (gp) ⅱ b ⅲ a fibrinogen will affect thrombosis.
(2) Inhibition of collagen-induced aggregation.
LAPP (Leech Antiplatelet Protein) is a specific inhibitor of collagen-induced platelet aggregation isolated from leech in Mexico.
Calin is a collagen-induced platelet aggregation inhibitor extracted from medical leeches, which can not only inhibit the interaction between collagen and platelets.
It can also prevent aggregation induced by the combination of VWF and collagen.
④ Effect on thrombin.
It has been proved that thrombin is the central enzyme in coagulation and hemostasis.
Thrombin can convert fibrinogen into fibrin, activate coagulation factors ⅴ and ⅶ and induce platelet activation.
In addition, it can stimulate vascular endothelial cells and muscle contraction, so that fiber cells proliferate.
It is known that hirudin is the strongest thrombin-specific inhibitor, and it forms a stable complex with equal molar ratio of non-valence bond with thrombin, thus making thrombin lose the ability to convert fibrinogen into fibrin, preventing thrombin-catalyzed hemostasis reaction and thrombin-induced platelet reaction, and achieving the purpose of anticoagulation.
The role of scalding leeches
Leech is a parasite that lives on the blood of animals or humans.
They have three jaws in their mouths. 1 The jaw is on the back and the two jaws are on the side, forming a triangle.
There are also fine teeth on the chin. Once they meet prey, leeches suck each other with powerful suckers on their heads and bite each other's skin with hundreds of fine teeth.
Medical leeches secrete a sticky saliva during biting, which is a very efficient anesthetic. The bitten person or animal will only feel a little acceptable pain, or even no feeling at all.
Humans have been using leeches to treat diseases for 3000 years, and the story of ancient humans using leeches to treat diseases has been branded on the tomb murals of ancient Egyptian pyramids.
China used leeches to treat diseases more than 2,000 years ago, which is recorded in Shennong Herbal Classic.
Li Shizhen, an imperial doctor in the Ming Dynasty, also believed that dried leeches contained hirudin and heparin, which had the functions of promoting blood circulation, dredging channels, resolving food stagnation, reducing swelling and detoxifying.
When people have cerebral hemorrhage, doctors can let leeches suck blood from the back of the patient's head and bones, which can reduce the congestion of organs.
At the same time, the saliva of leeches contains hirudin, which is an effective anticoagulant and can prevent vasoconstriction.
About Hirudo Treating Cerebral Infarction
Treating cerebral infarction and cerebral hemorrhage.
Cerebral infarction is intravascular coagulation and thrombosis. Leech has anticoagulant and thrombolytic effects, which should be beneficial to the treatment of the disease.
But in the initial stage of stroke, the condition can evolve from infarction to bleeding.
At the stage of infarction without bleeding, it is not appropriate to use the method of promoting blood circulation and removing blood stasis to anticoagulate and solubilize prematurely.
It should be used in the stage of definite infarction and stable condition.
What is the function of leeches? How to identify? leech
Also known as leech turtle
Sexual taste tropism: the taste is shouting, bitter and flat; Liver meridian.
Breaking blood and removing silt is powerful and effective.
Leech is poisonous, but it has a strong effect of breaking blood and removing blood stasis, and can treat amenorrhea and postpartum abdominal pain due to blood stasis. Leech also has the functions of removing blood stasis, relieving pain and setting bones.
"Herbal Yan Hui" records that "leeches are also drugs for expelling blood and removing blood stasis, which can store and accumulate blood and cure those who have no children and become dry."
Leech file
Leeches, also known as horse turtles, are distributed all over the country.
It belongs to leech family, and its medicinal part is dried leech, which is mostly caught in summer and autumn, washed, scalded to death with boiling water, cut into sections or dried at low temperature to obtain raw leech; Or stir-fry talcum powder with high fire, then put it into the leech section, scald it until it is crisp and rotten, and sieve off talcum powder to get the scalded leech.
You can also put fresh leeches in the swollen parts to suck blood and eliminate congestion.
Modern research has confirmed that the main nutrients in leeches include protein, peptides, trace elements and fatty acids.
Efficacy indication
Blood-breaking and silt-removing effects.
Indications: 1. Used for amenorrhea caused by blood stasis, postpartum blood stasis abdominal pain, etc.
2. Used for traumatic injury, fracture pain, etc.
3. For cerebral hemorrhage, intracranial hematoma or thrombocytosis.
Matters needing attention
1. Leech is poisonous, so use it with caution. The dosage of oral decoction is 3-6g, and the dosage of baking powder is 0.3-0.6g each time.
2. Pregnant women should not use it.
What does leech do? How to use it? Leech, a Chinese medicine name, is leech, leech or dried leech of Leech family.
It is salty, bitter and flat in nature, with little toxicity, and enters the liver meridian.
It has the effects of removing blood stasis, dredging channels and activating collaterals, and can be used for treating abdominal mass, amenorrhea due to blood stasis, traumatic injury and other diseases.
However, it should be noted that pregnant women and patients without blood stasis should ban leeches.
First of all, fresh leeches themselves have hirudin, which is a secretion of the head gland and a polypeptide. Its secretion contains a histamine-like substance, such as heparin and antithrombin.
As a traditional Chinese medicine leech, it has the effect of terminating pregnancy, especially suitable for early pregnancy.
Moreover, leech, a traditional Chinese medicine, also has anticoagulant effect, which can significantly inhibit platelet aggregation and reduce blood viscosity, thus preventing thrombosis.
In addition, leech can also improve the microcirculation of the body, absorb some hematoma caused by acute cerebral hemorrhage, relieve inflammation and edema around brain tissue, and relieve the increase of intracranial pressure, thus improving local circulation and facilitating the recovery of neurological function.
Secondly, leech can obviously reduce hyperlipidemia, hypercholesterolemia and triglycerides.
In addition, hirudin can inhibit the growth of tumor cells and liver cancer.
Because leech has a high anticoagulant effect, it is beneficial to be used as an anticancer drug, which can act on immunocompetent cells to infiltrate cancer tissues and kill cancer cells.
In addition, it is worth noting that some people with weak constitution or weak pulse should not use leeches.
Pregnant women and people with bleeding tendency can't use leeches.
There are also some anemia patients, and the anemia situation is often more serious after taking leeches.
Generally, when taking leeches, it is necessary to replenish qi and blood at the same time to prevent harm to the body.
To sum up, we know that leech, a traditional Chinese medicine, has many functions, which can obviously reduce hyperlipidemia and hypercholesterolemia and inhibit the growth of tumor cells.
However, in the process of using leeches, we should also pay attention. Some specific people must avoid using leeches. It is best for patients to use leeches under the guidance of doctors, and pay attention to tonifying qi and blood, so as not to cause harm to the body.
Which is better, raw leech powder or scalded leech? Generally speaking, the activity of hirudin, an effective component contained in leeches, will be inactivated at high temperature, so the effect of producing leech powder is better.
The leech-leech wide body sold in pharmacies does not contain hirudin after research, and the effect of promoting blood circulation has not changed much before and after decoction.
So if you only refer to leeches bought in pharmacies, there is little difference between them, but if you buy leeches dried at low temperature, the effect before and after decoction is very different.
So much for the introduction of the efficacy and function of scalding leeches. Thank you for taking the time to read the contents of this website. Don't forget to check the efficacy and function of scalding leeches and how to eat them.